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Turmeric is a spice with countless beneficial properties that have been attributed in particular to Curcumin as an active substance. Curcumin is a powerful antioxidant capable of activating various enzymes and enhancing the physiological antioxidant system and is therefore very useful in the prevention and treatment of diseases characterized by oxidative stress (aging, diabetes, cardiovascular diseases, neurodegenerative diseases, cancer).
Unlike many other antioxidants, Curcumin has a dual activity as it is able to both prevent the formation of free radicals and neutralize existing free radicals. Curcumin is a powerful anti-inflammatory and is very useful in the prevention and treatment of inflammatory diseases, especially at the gastrointestinal level, it improves the functionality of the stomach and intestine, it is useful in disorders such as colitis, pancreatitis, neurodegenerative diseases, cardiovascular diseases, autoimmune diseases, inflammatory bowel diseases (Crohn’s disease), obesity, diabetes, respiratory diseases such as asthma and bronchitis, psoriasis and cancer. According to a recent study, Curcumin in the body is transformed into a substance with neuroprotective capacity capable of reducing oxidative stress and neuroinflammation, improving neurological function. It can also prevent neurodegeneration typical of Parkinson’s disease and can be useful in Alzheimer’s disease as it maintains normal structure and function of cerebral vessels and synapses.
Curcumin, after oral ingestion, can exert regulatory effects on the intestinal microbiota, helping to improve well-being and problems related to alterations of this balance. Curcumin supplementation can also be useful in the treatment of type 2 diabetes mellitus: a 2019 study showed that treating diabetic mice with Curcumin resulted in improved insulin sensitivity, reduced blood sugar levels, and improved dyslipidemia.
Curcumin is very effective in the treatment of cardiovascular diseases through several mechanisms: reduction of plasma lipids, increase in HDL levels, reduction of lipid peroxidation, reduction of atherosclerotic lesions, and improvement of endothelial function. There is evidence in the literature of the effectiveness of Curcumin especially in the treatment of the following types of tumors: Breast cancer, Lung cancer, Hematological and lymphatic system tumors, Stomach cancer, Oral cavity cancer, Colorectal cancer, Pancreatic cancer, Liver cancer, Prostate cancer, Brain tumors, Mesothelioma, Fibrosarcoma, and Melanoma. Various studies have shown that Curcumin is also an excellent aid to counteract the typical side effects of chemotherapy such as gastrointestinal toxicity, cardiotoxicity and hepatotoxicity.
Despite all the benefits it brings to health and the numerous properties of Turmeric, one of the main critical issues of Curcumin is its poor bioavailability. The liposomal solution allows maximum absorption. The liposome formulation also allows you to avoid all those products that contain “piperine”, a highly inflammatory and irritating substance, not recommended for those suffering from gastric disorders or for cancer patients.
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