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Fito Brain Plus

40,00 

Food supplement based on Ginkgo and dry extract of Red Grapes.
Promotes memory and cognitive functions.
PACKAGE: 90 vegetable capsules
USEFUL FOR
• promote memory and cognitive functions even in periods of intense study and work • protect against oxidative stress • promote well-being in case of mental overload also associated with migraine
PLUS
• vegetable formula • with botanical extracts • synergistic action • does not contain sugars • without artificial colorants and flavors • without ingredients of animal origin • gluten-free and lactose-free • with natural excipients
HOW TO USE
It is recommended to take 3 capsules a day to be swallowed with plenty of water.
WARNINGS
Do not exceed the recommended daily dose. Food supplements should not be considered a substitute for a varied, balanced diet and a healthy lifestyle. Keep out of reach of children under three years of age. Store in a cool, dry place, away from light. The minimum shelf life refers to the product correctly stored in its intact packaging.
Additional warning: if you are taking anticoagulant or antiplatelet drugs, consult your doctor before taking the product. The use of the product is not recommended during pregnancy and breastfeeding.
Important warning: in case of alterations in liver or biliary function or gallstones, the use of the product is not recommended. Do not use during pregnancy and breastfeeding. Do not use for prolonged periods without consulting your doctor. If you are taking medications, it is advisable to seek the advice of your doctor.
EAN: 8056046912038

The synergy of substances that promote brain health improves cognitive functions and protects against brain degenerative forms. The FITO BRAIN PLUS formula, based on Boswellia, Ginko, PEA, Curcumin, Quercitin and Red Grapes, was created with the aim of promoting mental health and preventing various forms of neuronal degenerative disease.

Ginko-Biloba has the property of stimulating the blood microcirculation of the brain, improving its brain activity and has a neuroprotective action, significantly improving memory consolidation in both young and elderly subjects: in fact, it is often used against memory disorders and for conditions that, especially in old age, are associated with a reduction in blood flow to the brain (such as headaches, dizziness and vertigo, tinnitus, difficulty concentrating and mood disorders). It is also used in other problems associated with circulation disorders (such as leg pain while walking, typical of claudication, and Raynaud’s syndrome).

It is useful in the treatment of tinnitus and vertigo syndromes of vascular origin. Scientific evidence suggests that Ginkgo extract could be really effective in cases of anxiety, to improve mental performance, in cases of dementia, against vision problems associated with diabetes, against glaucoma, to combat premenstrual syndrome, against schizophrenia and dyskinesia.

Ginko, together with Red Grapes, has antioxidant properties and they act in synergy to improve cerebral blood microcirculation and therefore blood flow. Together they protect against oxidative stress. Vitis Vinifera has been used for thousands of years for its nutritional and medicinal properties and is traditionally used in the treatment of capillary bleeding, edema and inflammation. Red Vine is particularly appreciated for its antioxidant and vasoprotective properties, has also shown beneficial effects on memory and cognitive functions and contributes to brain health.

The Flavonoids and Anthocyanins present in Red Vine fight free radicals, protecting brain cells from oxidative stress, preventing cognitive deterioration and improving neuronal function.

PEA (Palmitoylethanolamide), the discovery of whose mechanism of action is due to Nobel Prize winner Prof. Levi-Montalcini, has an anti-inflammatory action on all brain connections and has cannabinergic effects. The structural analogy with the endocannabinoid molecule AEA (Anandamide) gives the lipid the ability to bind peripheral CB2 cannabinoid receptors, positively modulating the expression of these receptors. Curcumin, on the other hand, is able to cross the blood-brain barrier and is a powerful anti-inflammatory. Quercetin helps promote neurogenesis in the hippocampus area of ​​the brain responsible for learning and memory function. Finally, Boswellic Acids have a strong anti-inflammatory action, acting with a mechanism similar to the NSAID drug, but without causing side effects, and are useful in the reabsorption of cerebral edema.

Diamond BJ, Bailey MR. Ginkgo biloba: indications, mechanisms, and safety. Psychiatr Clin North Am. 2013 Mar;36(1):73-83. doi: 10.1016/j.psc.2012.12.006. PMID: 23538078 – Link

Nassiri-Asl M, Hosseinzadeh H. Review of the Pharmacological Effects of Vitis vinifera (Grape) and its Bioactive Constituents: An Update. Phytother Res. 2016 Sep;30(9):1392- 403. doi: 10.1002/ptr.5644. Epub 2016 May 16. PMID: 27196869 – Link

Tabeshpour J, Mehri S, Shaebani Behbahani F, Hosseinzadeh H. Protective effects of Vitis vinifera (grapes) and one of its biologically active constituents, resveratrol, against natural and chemical toxicities: A comprehensive review. Phytother Res. 2018 Nov;32(11):2164- 2190. doi: 10.1002/ptr.6168. Epub 2018 Aug 8. PMID: 30088293 – Link

Qingwang Lian 1, Yongsheng Nie 1, Xiaoyou Zhang 2, Bo Tan 1, Hongying Cao 1, Wenling Chen 2, Weiming Gao 2, Jiayi Chen 1, Zhijian Liang 1, Huangling Lai 1, Siming Huang 1, Yifei Xu 1, Weiwen Jiang 1, Ping Huang 1 “Effects of grape seed proanthocyanidin on Alzheimer’s disease in vitro and in vivo” PubMed 2016 – Link

Colizzi M, Bortoletto R, Colli C, Bonomo E, Pagliaro D, Maso E, Di Gennaro G, Balestrieri M. Therapeutic effect of palmitoylethanolamide in cognitive decline: A systematic review and preliminary meta-analysis of preclinical and clinical evidence. Front Psychiatry. 2022 Oct 28;13:1038122. doi: 10.3389/fpsyt.2022.1038122. PMID: 36387000; PMCID: PMC9650099 – Link

Askarizadeh A, Barreto GE, Henney NC, Majeed M, Sahebkar A. Neuroprotection by curcumin: A review on brain delivery strategies. Int J Pharm. 2020 Jul 30;585:119476. doi: 10.1016/j.ijpharm.2020.119476. Epub 2020 May 27. PMID: 32473377 – Link

Ma ZX, Zhang RY, Rui WJ, Wang ZQ, Feng X. Quercetin alleviates chronic unpredictable mild stress-induced depressive-like behaviors by promoting adult hippocampal neurogenesis via FoxG1/CREB/ BDNF signaling pathway. Behav Brain Res. 2021 May 21;406:113245. doi: 10.1016/j.bbr.2021.113245. Epub 2021 Mar 18. PMID: 33745981 – Link

Kirste S, Treier M, Wehrle SJ, Becker G, Abdel-Tawab M, Gerbeth K, Hug MJ, Lubrich B, Grosu AL, Momm F. Boswellia serrata acts on cerebral edema in patients irradiated for brain tumors: a prospective, randomized, placebo-controlled, double-blind pilot trial. Cancer. 2011 Aug 15;117(16):3788-95. doi: 10.1002/cncr.25945. Epub 2011 Feb 1. PMID: 21287538 – Link

POSSIBLE COMBINATIONS
Melatonin, Pea, Resveralip
INGREDIENTS
Boswellia (Boswellia serrata Roxb. ex Colebr.) gum-resin dry extract tit. at 65% in Broswellic Acids; coating agent: Hydroxypropyl methylcellulose (capsule); Ginkgo (Ginkgo Biloba L.) leaves dry extract tit. at 24% in Ginkgoflavonoid Glycosides; Micronized Palmitoylethanolamide (PEA-m); Curcuminoids (from Curcuma longa L., rhizome); Quercitin (from Sophora Japonica L., flowers); Red Grape (Vitis vinifera L.) seeds dry extract tit. at 95% in Proanthocyanidins; bulking agent: cellulose; anti-caking agents: Magnesium salts of fatty acids.
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