{"id":17395,"date":"2025-03-17T11:16:10","date_gmt":"2025-03-17T10:16:10","guid":{"rendered":"https:\/\/www.elevecosmetic.com\/shop\/pea\/"},"modified":"2025-04-03T15:35:41","modified_gmt":"2025-04-03T13:35:41","slug":"pea","status":"publish","type":"product","link":"https:\/\/www.elevecosmetic.com\/en\/shop\/pea\/","title":{"rendered":"Pea"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-post\" data-elementor-id=\"17395\" class=\"elementor elementor-17395 elementor-17346\">\n\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-c4aecbb e-con-boxed e-con\" data-id=\"c4aecbb\" data-element_type=\"container\" data-settings=\"{&quot;content_width&quot;:&quot;boxed&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-f387d31 elementor-widget elementor-widget-toggle\" data-id=\"f387d31\" data-element_type=\"widget\" data-widget_type=\"toggle.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<style>\/*! elementor - v3.12.1 - 02-04-2023 *\/\n.elementor-toggle{text-align:left}.elementor-toggle .elementor-tab-title{font-weight:700;line-height:1;margin:0;padding:15px;border-bottom:1px solid #d5d8dc;cursor:pointer;outline:none}.elementor-toggle .elementor-tab-title .elementor-toggle-icon{display:inline-block;width:1em}.elementor-toggle .elementor-tab-title .elementor-toggle-icon svg{-webkit-margin-start:-5px;margin-inline-start:-5px;width:1em;height:1em}.elementor-toggle .elementor-tab-title .elementor-toggle-icon.elementor-toggle-icon-right{float:right;text-align:right}.elementor-toggle .elementor-tab-title .elementor-toggle-icon.elementor-toggle-icon-left{float:left;text-align:left}.elementor-toggle .elementor-tab-title .elementor-toggle-icon .elementor-toggle-icon-closed{display:block}.elementor-toggle .elementor-tab-title .elementor-toggle-icon .elementor-toggle-icon-opened{display:none}.elementor-toggle .elementor-tab-title.elementor-active{border-bottom:none}.elementor-toggle .elementor-tab-title.elementor-active .elementor-toggle-icon-closed{display:none}.elementor-toggle .elementor-tab-title.elementor-active .elementor-toggle-icon-opened{display:block}.elementor-toggle .elementor-tab-content{padding:15px;border-bottom:1px solid #d5d8dc;display:none}@media (max-width:767px){.elementor-toggle .elementor-tab-title{padding:12px}.elementor-toggle .elementor-tab-content{padding:12px 10px}}.e-con-inner>.elementor-widget-toggle,.e-con>.elementor-widget-toggle{width:var(--container-widget-width);--flex-grow:var(--container-widget-flex-grow)}<\/style>\t\t<div class=\"elementor-toggle\" role=\"tablist\">\n\t\t\t\t\t\t\t<div class=\"elementor-toggle-item\">\n\t\t\t\t\t<div id=\"elementor-tab-title-2551\" class=\"elementor-tab-title\" data-tab=\"1\" role=\"tab\" aria-controls=\"elementor-tab-content-2551\" aria-expanded=\"false\">\n\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-toggle-icon elementor-toggle-icon-left\" aria-hidden=\"true\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-toggle-icon-closed\"><svg class=\"e-font-icon-svg e-fas-caret-right\" viewBox=\"0 0 192 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M0 384.662V127.338c0-17.818 21.543-26.741 34.142-14.142l128.662 128.662c7.81 7.81 7.81 20.474 0 28.284L34.142 398.804C21.543 411.404 0 402.48 0 384.662z\"><\/path><\/svg><\/span>\n\t\t\t\t\t\t\t\t<span class=\"elementor-toggle-icon-opened\"><svg class=\"elementor-toggle-icon-opened e-font-icon-svg e-fas-caret-up\" viewBox=\"0 0 320 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M288.662 352H31.338c-17.818 0-26.741-21.543-14.142-34.142l128.662-128.662c7.81-7.81 20.474-7.81 28.284 0l128.662 128.662c12.6 12.599 3.676 34.142-14.142 34.142z\"><\/path><\/svg><\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t<a href=\"\" class=\"elementor-toggle-title\">Scientific Insights<\/a>\n\t\t\t\t\t<\/div>\n\n\t\t\t\t\t<div id=\"elementor-tab-content-2551\" class=\"elementor-tab-content elementor-clearfix\" data-tab=\"1\" role=\"tabpanel\" aria-labelledby=\"elementor-tab-title-2551\"><p>PEA is a physiological substance normally produced by many cells in our body. In particular, it is found in very high concentrations in brain tissue and is synthesized from the lipid components of cell membranes. It is normally present in many of the foods we eat every day, such as eggs, peas, tomatoes and soy. As an active ingredient, it was identified in 1957 by Nobel Prize winner Rita Levi Montalcini, who interpreted its mechanism of action in 1993. At the body level, PEA works as a biological modulator of chronic pain of various types linked to the activation of inflammatory and painful processes. In particular, PEA limits the release of pro-inflammatory and painful mediators by blocking mast cells and the activation of cells at the level of the spinal cord: this makes it extremely effective in containing pain associated with an inflammatory state.<\/p>\n<p>Since PEA is an endogenous modulator, i.e. a substance normally produced by our body, no side effects or interactions with other drugs have been reported, making it an effective remedy for the treatment of numerous pathologies with chronic pain that, as a rule, respond poorly to standard pharmacological therapies. The exogenous administration of PEA therefore allows to reintegrate the correct physiological reserves of this substance that can be altered or reduced by particular situations in the body.<\/p>\n<p>This molecule demonstrates numerous beneficial activities for the body including: a modulating action on inflammatory processes that contributes to the control of unwanted inflammatory responses, thus promoting homeostasis; an effective analgesic action in conditions of chronic and neuropathic pain; antimicrobial properties that contribute to the response of the immune system against pathogens, including viral or drug-resistant agents; modulating the immune response helping to maintain balance in the immune system and reducing chronic inflammation.<\/p>\n<p>PEA\u2019s ability to protect nerve cells from damage and stress is particularly useful in preventing neurodegeneration. In chronic pathological situations, exogenous supplementation with PEA has been shown to be beneficial in addressing imbalances and maintaining homeostasis.<\/p>\n<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-c612959 e-con-boxed e-con\" data-id=\"c612959\" data-element_type=\"container\" data-settings=\"{&quot;content_width&quot;:&quot;boxed&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-bb22a4f elementor-widget elementor-widget-toggle\" data-id=\"bb22a4f\" data-element_type=\"widget\" data-widget_type=\"toggle.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-toggle\" role=\"tablist\">\n\t\t\t\t\t\t\t<div class=\"elementor-toggle-item\">\n\t\t\t\t\t<div id=\"elementor-tab-title-1961\" class=\"elementor-tab-title\" data-tab=\"1\" role=\"tab\" aria-controls=\"elementor-tab-content-1961\" aria-expanded=\"false\">\n\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-toggle-icon elementor-toggle-icon-left\" aria-hidden=\"true\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-toggle-icon-closed\"><svg class=\"e-font-icon-svg e-fas-caret-right\" viewBox=\"0 0 192 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M0 384.662V127.338c0-17.818 21.543-26.741 34.142-14.142l128.662 128.662c7.81 7.81 7.81 20.474 0 28.284L34.142 398.804C21.543 411.404 0 402.48 0 384.662z\"><\/path><\/svg><\/span>\n\t\t\t\t\t\t\t\t<span class=\"elementor-toggle-icon-opened\"><svg class=\"elementor-toggle-icon-opened e-font-icon-svg e-fas-caret-up\" viewBox=\"0 0 320 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M288.662 352H31.338c-17.818 0-26.741-21.543-14.142-34.142l128.662-128.662c7.81-7.81 20.474-7.81 28.284 0l128.662 128.662c12.6 12.599 3.676 34.142-14.142 34.142z\"><\/path><\/svg><\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t<a href=\"\" class=\"elementor-toggle-title\">Bibliography<\/a>\n\t\t\t\t\t<\/div>\n\n\t\t\t\t\t<div id=\"elementor-tab-content-1961\" class=\"elementor-tab-content elementor-clearfix\" data-tab=\"1\" role=\"tabpanel\" aria-labelledby=\"elementor-tab-title-1961\"><p class=\"p1\">Skaper S.D., Buriani A., Dal Toso R., Petrelli L., Romanello S., Facci L., Leon A. 1996 \u2013<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/8633002\/\">\u00a0Link<\/a><\/p>\n<p class=\"p1\">The ALIAmide palmitoylethanolamide and cannabinoids, but not anandamide, are protective in a delayed postglutamate paradigm of excitotoxic death in cerebellar granule neurons \u2013<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/8633002\/\">\u00a0Link<\/a><\/p>\n<p class=\"p1\">Proc Natl Acad Sci U S A. 30;93(9):3984-9. Luongo L, Starowicz K, Maione S, Di Marzo V. Allodynia Lowering Induced by Cannabinoids and Endocannabinoids (ALICE). Pharmacol Res. 2017;119:272-277 \u2013\u00a0<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/28237514\/\">Link<\/a><\/p>\n<p class=\"p1\">Levi-Montalcini R1, Skaper SD, Dal Toso R, Petrelli L, Leon A. Nerve growth factor: from neurotrophin to neurokine. Trends Neurosci. 1996;19(11):514-20 \u2013\u00a0<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/8931279\/\">Link<\/a><\/p>\n<p class=\"p1\">Paul Clayton, Mariko Hill, Nathasha Bogoda, Silma Subah, and Ruchitha Venkatesh. Palmitoylethanolamide: A Natural Compound for Health Management. Int J Mol Sci. 2021 May; 22(10): 5305 \u2013\u00a0<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34069940\/\">Link<\/a><\/p>\n<p class=\"p1\">Bekir Berker Artukoglu, Chad Beyer, Adi Zuloff-Shani, Ephraim Brener, Michael Howard Bloch. Efficacy of Palmitoylethanolamide for Pain: A Meta-Analysis. Pain Physician. 2017 Jul;20(5):353-362 \u2013\u00a0<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/28727699\/\">Link<\/a><\/p>\n<p class=\"p1\">Lo Verme J., Fu J., Astarita G., La Rana G., Russo R., Calignano A., Piomelli D. 2005. The nuclear receptor peroxisome proliferator-activated receptor-alpha mediates the antiinflammatory actions of palmitoylethanolamide. Mol Pharmacol. 67(1):15-9. 1 \u2013\u00a0<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/15465922\/\">Link<\/a><\/p>\n<p class=\"p1\">Skaper S.D., Buriani A., Dal Toso R., Petrelli L., Romanello S., Facci L., Leon A. 1996. The ALIAmide palmitoylethanolamide and cannabinoids, but not anandamide, are protective in a delayed postglutamate paradigm of excitotoxic death in cerebellar granule neurons. Proc Natl Acad Sci U S A. 30;93(9):3984-9 \u2013\u00a0<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/8633002\/\">Link<\/a><\/p>\n<p class=\"p1\">Paul Clayton 1, Mariko Hill 2, Nathasha Bogoda 2, Silma Subah 2, Ruchitha Venkatesh 3 \u201cPalmitoylethanolamide: A Natural Compound for Health Management\u201d PubMed 2021 \u2013\u00a0<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34069940\/\">Link<\/a><\/p>\n<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-136a25c e-con-boxed e-con\" data-id=\"136a25c\" data-element_type=\"container\" data-settings=\"{&quot;content_width&quot;:&quot;boxed&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-032fc7b elementor-widget elementor-widget-image\" data-id=\"032fc7b\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<style>\/*! elementor - v3.12.1 - 02-04-2023 *\/\n.elementor-widget-image{text-align:center}.elementor-widget-image a{display:inline-block}.elementor-widget-image a img[src$=\".svg\"]{width:48px}.elementor-widget-image img{vertical-align:middle;display:inline-block}<\/style>\t\t\t\t\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"1536\" height=\"442\" src=\"https:\/\/www.elevecosmetic.com\/wp-content\/uploads\/2025\/03\/tab-en-niki-natural-alchemy2-1536x442.jpg\" class=\"attachment-1536x1536 size-1536x1536 wp-image-17821\" alt=\"\" srcset=\"https:\/\/www.elevecosmetic.com\/wp-content\/uploads\/2025\/03\/tab-en-niki-natural-alchemy2-1536x442.jpg 1536w, https:\/\/www.elevecosmetic.com\/wp-content\/uploads\/2025\/03\/tab-en-niki-natural-alchemy2-300x86.jpg 300w, https:\/\/www.elevecosmetic.com\/wp-content\/uploads\/2025\/03\/tab-en-niki-natural-alchemy2-1024x294.jpg 1024w, https:\/\/www.elevecosmetic.com\/wp-content\/uploads\/2025\/03\/tab-en-niki-natural-alchemy2-768x221.jpg 768w, https:\/\/www.elevecosmetic.com\/wp-content\/uploads\/2025\/03\/tab-en-niki-natural-alchemy2-680x196.jpg 680w, https:\/\/www.elevecosmetic.com\/wp-content\/uploads\/2025\/03\/tab-en-niki-natural-alchemy2.jpg 2000w\" sizes=\"auto, (max-width: 1536px) 100vw, 1536px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-0ade658 e-con-boxed e-con\" data-id=\"0ade658\" data-element_type=\"container\" data-settings=\"{&quot;content_width&quot;:&quot;boxed&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-1532204 elementor-widget elementor-widget-text-editor\" data-id=\"1532204\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<style>\/*! elementor - v3.12.1 - 02-04-2023 *\/\n.elementor-widget-text-editor.elementor-drop-cap-view-stacked .elementor-drop-cap{background-color:#69727d;color:#fff}.elementor-widget-text-editor.elementor-drop-cap-view-framed .elementor-drop-cap{color:#69727d;border:3px solid;background-color:transparent}.elementor-widget-text-editor:not(.elementor-drop-cap-view-default) .elementor-drop-cap{margin-top:8px}.elementor-widget-text-editor:not(.elementor-drop-cap-view-default) .elementor-drop-cap-letter{width:1em;height:1em}.elementor-widget-text-editor .elementor-drop-cap{float:left;text-align:center;line-height:1;font-size:50px}.elementor-widget-text-editor .elementor-drop-cap-letter{display:inline-block}<\/style>\t\t\t\t<h6>POSSIBLE COMBINATIONS<br \/>\nMelatonin, Resveralip<\/h6>\n<h6>INGREDIENTS<br \/>\nPEA (Palmitoylethanolamide), Hydroxypropylmethylcellulose (capsule), bulking agent: Microcrystalline Cellulose; anti-caking agents: Magnesium salts of fatty acids.<\/h6>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>Food supplement based on Palmitoylethanolamide.<br \/>\nReduces pain and inflammation naturally.<\/p>\n<p>PACKAGE: 60 vegetable capsules<\/p>\n<p>USEFUL FOR<br \/>\n\u2022 promote osteoarticular and cartilage well-being, \u2022 provide support in chronic inflammatory conditions associated with pain (neuropathies, osteoarthritis, muscle stiffness, sciatica, carpal tunnel syndrome)<\/p>\n<p>PLUS<br \/>\n\u2022 high-dose formula \u2022 contains no sugars \u2022 no artificial colors and flavors \u2022 no ingredients of animal origin \u2022 no gluten and no lactose \u2022 with natural excipients<\/p>\n<p>HOW TO USE It is recommended to take two capsules a day to be swallowed with a little water.<\/p>\n<p>WARNINGS Do not exceed the recommended daily dose. Food supplements should not be considered a substitute for a varied, balanced diet and a healthy lifestyle. Keep out of reach of children under three years of age.<br \/>\nEAN: 8056046911987<\/p>\n","protected":false},"featured_media":16382,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"product_cat":[229,232],"product_tag":[237],"class_list":["post-17395","product","type-product","status-publish","has-post-thumbnail","hentry","product_cat-molecole-endogenous","product_cat-niki-natural-alchemy-en","product_tag-molecole-endogenous"],"_links":{"self":[{"href":"https:\/\/www.elevecosmetic.com\/en\/wp-json\/wp\/v2\/product\/17395","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.elevecosmetic.com\/en\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/www.elevecosmetic.com\/en\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/www.elevecosmetic.com\/en\/wp-json\/wp\/v2\/comments?post=17395"}],"version-history":[{"count":9,"href":"https:\/\/www.elevecosmetic.com\/en\/wp-json\/wp\/v2\/product\/17395\/revisions"}],"predecessor-version":[{"id":17825,"href":"https:\/\/www.elevecosmetic.com\/en\/wp-json\/wp\/v2\/product\/17395\/revisions\/17825"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.elevecosmetic.com\/en\/wp-json\/wp\/v2\/media\/16382"}],"wp:attachment":[{"href":"https:\/\/www.elevecosmetic.com\/en\/wp-json\/wp\/v2\/media?parent=17395"}],"wp:term":[{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/www.elevecosmetic.com\/en\/wp-json\/wp\/v2\/product_cat?post=17395"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/www.elevecosmetic.com\/en\/wp-json\/wp\/v2\/product_tag?post=17395"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}